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In contrast, in diseases characterised by mitochondrial dysfunction and bioenergetic failure (often reflected by reduced FDG-PET signal), elevated iron may instead represent a compensatory response to functional iron deficiency rather than a pathogenic surplus
Taking them together provides a more comprehensive approach to cellular wellness than taking either one alone
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doi: 10.1016/j.neubiorev.2009.07.005
10.1016/j.bcp.2017.10.007 98
