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10.3390/antiox12061172 51 CharisisS.NtanasiE.YannakouliaM.AnastasiouC

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NE-producing neurons in the LC widely project to many regions of the CNS to modulate functions such as attention, arousal, pain, mood, and stress responses ( 2.2 Dysregulation of the HPA axis aggravates the progression of PD The hypothalamicpituitaryadrenal (HPA) axis is a critical neuroendocrine pathway within the MGBA

Combinatorial Approaches Integrating nanobioconjugates with small-molecule inhibitors could harness synergistic effects, balancing the rapid action of small molecules with the targeted precision of nanocarriers