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Metabolites and the tumour microenvironment: from cellular mechanisms to systemic metabolism

The major phytocannabinoids are delta-9-tetrahydrocannabinol (delta-9-THC), cannabidiol (CBD), and cannabigerol (CBG)

Signal 20 (1), 61

The siP-Syn peptide administration The polypeptide we used was based on a previous study [13]

Furthermore, SAM is not sensed by dSamtor but by the Umet protein, which binds to GATOR2, 99 demonstrating that flies and vertebrates independently evolved unrelated, mechanistically distinct sensors that converge upon the same metabolite
