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The results showed that MDA levels in group B were the highest compared with the other groups, indicating that ROS generated oxidative stress and damage

35,36 Kong et al

pylori), a type of bacteria linked with many stomach ulcers

The interplay of local (within the diseased liver) and systemic inflammation, stemming from portal hypertension and alterations in the gut microbiome, alongside heightened levels of circulating cytokines, disrupts hepatic vagal neurogenic responses and impacts cerebral endothelial cells, giving rise to neuroinflammation