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Description
Cortisol, the major chronic stress hormone, is a glucocorticoid released in response to various stresses that induces the degradation of proteins see the Hypothelamic-Pituitary-Adrenal Axis

abnormal -syn in turn impairs mitochondrial function and triggers neuroinflammation

In short, its found virtually everywhere in the human body, and its essential to our healthy existence
By changing the cellular environment and the accessibility of iron, which is essential for macrophage activity, ferroptosis might affect macrophage polarization

J Clin Pharmacol
