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In these cases, the issue may not be classic high-histamine undermethylation

ROS cause lipid peroxidation, protein oxidation, and DNA damage, leading to cellular dysfunction and apoptosis

There has been a reduced intake of saturated fat accompanied by an increase in n-6 PUFA consumption, particularly linoleic acid and arachidonic acid

A general finding is that obese patients fulfilling criteria for MetS together with low IGF-1 plasma levels tend to develop a worse cardiovascular disease outcome than those with mid-normal to high-normal IGF-1 levels [213]

3a) and confirmed the loss of the GLAST gene by PCR analysis (Fig
