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Ascorbate requirements of smokers based on intake and serum concentrations show that smokers may require as much as three times the dose of ascorbate than nonsmokers to avoid risk of efficiency [3032, 34]

Higher baseline deficiency risk in the target population Research has consistently shown that individuals with obesity have higher rates of B12 deficiency compared to the general population

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ISBN 978-92-4-156545-5 (2017)