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doi: 10.3389/fphys.2022.885802 Received 28 February 2022 Accepted 11 April 2022 Published 22 April 2022 Volume 13 - 2022 Edited by John William Larkin, Fresenius Medical Care, United States Reviewed by Stefan Rudloff, University of Bern, Switzerland Yingfeng Shi, Tongji University, China Updates Copyright 2022 Krediet