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Chapter 22: Autoimmune diseases, Pernicious Anemia (Vitamin B12 Deficiency) PERNICIOUS ANAEMIA (PA) Definition This is megaloblastic anemia due to deficiency of vitamin B12, because of malabsorption, which is believed as an autoimmune phenomenon to gastric parietal cells and their products

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Prompt parenteral administration of vitamin B 12prevents progression of neurologic damage