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Topical phenylephrine, used in-office for iris dilation, and its prodrugs dipivefrin and apraclonidine have been documented to induce AACG [2] Topical anticholinergic/cycloplegics agents used for pupillary dilation may also lead to AACG [2] [1] Botulinum act at peripheral cholinergic synapses, inhibiting the release of acetylcholine
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Vibralactone Vibralactone secreted from Boreostereum virens microfungi is a scarce fused -lactone-type metabolite, covalently but reversibly transforms the active site serine of the enzyme via acylation by the blactone
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