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[23] How does this occur

The adverse effects frequently are delayed (1-2 days) reactions typified by one or more of the following symptoms: arthralgia, backache, chills, dizziness, moderate to high fever, headache, malaise, myalgia, nausea, and vomiting

Achenbach, H., et al., Pharmacokinetics of AlphaLipoic Acid in Subjects With Severe Kidney Damage and EndStage Renal Disease
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Unlike skeletal muscle, leucocytes are largely dependent of the glutamine synthetized and released into the blood by the skeletal muscle, to satisfy their metabolic requirements [5, 152]
