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[48] The most recent edition of the International Classification of Diseases, ICD-11, currently identifies three types of narcolepsy: type 1 narcolepsy, type 2 narcolepsy, and unspecified narcolepsy

Fibroblast growth factor 21 FGF21 is a peptide hormone primarily released by the liver during starvation that can regulate peripheral glucose tolerance and lipid metabolism via its direct activation of FGF receptors on the plasma membrane of target cells (498)

These metabolic disturbances activate several pathogenic pathways that contribute to neuronal dysfunction and death, ultimately manifesting as DPN

This statement is particularly true when their relatives are on the maternal side of the family
