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This may reflect a level of redundancy in the routes that GLUT1 may take to recycle back to the cell surface once the essential SNX27 and Retromer-orchestrated retrieval fate decision has been made

Furthermore, Song et al (208) found in a cell model of oxalate-induced kidney stones that CaOx crystals can induce ferroptosis through autophagy, thereby exacerbating kidney damage

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Autoimmune-specific cautions The most important caution for lupus researchers is this: immune-stimulating peptides must be approached with extreme care

Ferroptosis is iron-dependent, iron can be involved in the Fenton reaction and also act as a cofactor to promote oxidative enzymes to engage in reactive oxygen species generation, but the role of executive factors downstream of lipid oxidation has not been elucidated by current studies (206)