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In infants known to be G6PD-deficient, prevention of severe hyperbilirubinemia by administration of a single IM dose of Sn-mesoporphyrin, an inhibitor of heme oxygenase, is highly effective and appears safe

doi: 10.1002/14651858.CD003868.pub3

(2002) Influence of the period-dependent circadian clock on diurnal, circadian, and aperiodic gene expression in Drosophila melanogaster

The questions were extensive, so a red herring question was asked at the final visit to gauge accuracy and compliance

644,645 Two phase III trials (EMERGE and ENGAGE) on another anti-A mAb, aducanumab, were stopped due to meeting prespecified futility criteria, although it was later recognized that some assumptions of the analysis were violated and inaccurately predicted the final outcomes