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These possible agents/inhibitors carry out their anti-tumor activity ( Receptor tyrosine kinase (RTK) inhibitors have been investigated for treatment options in TNBC

We speculate that the tardigrade avoids excessive destruction of cellular components after severe stress by suppressing autophagy induction and this might be beneficial to resume cellular activity by using partially damaged biomolecules after rehydration

Slower escalation with better tolerance produces better long-term adherence and results than aggressive dosing that causes misery

Other studies suggest that D3 activity may be anti-inflammatory in mast cells, as there is a negative correlation between the numbers of D3-expressing mast cells in synovial fluid and disease severity in RA (Xue, Li et al., 2018)

doi: 10.1038/s41565-023-01548-3