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Detected P-NA is in direct proportion to caspase-3 concentration

These mechanisms elucidate the pathological underpinnings of ferroptosis across a spectrum of diseases and suggest potential therapeutic targets

In contrast to these findings, skeletal muscle-specific TSC1-deficient mice (TSCmKO), which show sustained activation of mTORC1, developed a late-onset myopathy related to impaired autophagy [62]

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