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The most common thing you might notice is mild redness, tenderness, or slight swelling where the needle went in, and that usually settles quickly

This reinforces the need for carefully titrated regimens, especially in clinical settings where circadian timing (chronopharmacology) may dictate efficacy

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Maedica 5(2):116 [PMC free article] [PubMed] [Google Scholar] Vagney M, Desquilbet L, Reyes-Gomez E, Delisle F, Devauchelle P, Rodriguez-Pieiro MI, Rosenberg D, de Fornel-Thibaud P (2018) Survival times for cats with hyperthyroidism treated with a 3.35 mCi iodine-131 dose: a retrospective study of 96 cases