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Suppression of Ectopic Migration: Neural stem cell (NSC) transplantation into SE models significantly reduces mossy fiber sprouting (MFS) area by 58%, indirectly indicating inhibition of newborn neuron ectopic migration (120, 121)

153 In our research, SD is found to reduce BDNF levels and induce depressive-like behaviors in the sorted astrocytes from GFAP-GFP transgenic mice by activating the NLRP3 inflammasome

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The therapeutic promise of AST lies not only in its molecular potency but also in its potential integration into multi-target interventions for complex neurodegenerative disorders