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Various plant derivatives, such as alkaloids, flavonoids, and terpenoids, have been extensively addressed for their anti-proliferative effects on multiple cancer types [113]
Ann Neurol 1989;26:456

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TNF- has been shown, mainly in experimental ED models and chronic inflammatory or metabolic conditions, to activate caspase-dependent apoptotic pathways while inhibiting the PI3K/Akt survival pathway (134)

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