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In addition, alcohol actually stimulates the production of more pancreatic enzymes so this just adds more pressure and swelling to the connection point of the pancreas and duodenum Other causes include tissue ischemia related to trauma or surgery, pancreatic tumors, third-trimester pregnancy, infections, elevated calcium levels, and hyperlipidemia

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Since then, several antiangiogenic therapies, mainly targeting VEGF signaling pathway have been developed and approved for the treatment of a variety of tumors (Table 1)

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J., Crompton, M

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