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As for the different sex-related activities of metabolizing enzymes, the specific activity of the catabolic enzyme gamma-glutamyltranspeptidase in female mice was 73% of that in male mice, suggesting that the faster glutathione turnover in males could account for the higher susceptibility to oxidative injury [64]

A recent Cochrane review which performed network meta-analysis of RCTs using cholinesterase inhibitors found varying quality evidence that donepezil and galantamine may improve cognition compared to placebo, but the effect may not be sufficiently large to be clinically important (703)

doi: 10.1016/j.bbaexp.2005.03.003

[Vitamin C and prevention of reflex sympathetic dystrophy following surgical management of distal radius fractures]