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For warfarin: increase INR checks from monthly to biweekly for the first month, then weekly if any bruising or bleeding signs appear
Marks N., Stern F., Kastin A.J., and Coy D.H., 1977

In contrast to the neuroprotection role of SIRT1, SIRT2 upregulation is toxic to neuronal cells

Micu et al., 2016, 2018), oxidative stress (Mahad et al., 2008), excitotoxic mechanisms (Joshi et al., 2014

2010;5:e8976
