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[DOI] [PMC free article] [PubMed] [Google Scholar] Ricci C, Ruscica M, Camera M, Rossetti L, Macchi C, Colciago A, Zanotti I, Lupo MG, Adorni MP, Cicero AFG, Fogacci F, Corsini A, Ferri N, 2018

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The CiticOline Brain Injury Trial (COBRIT) has enrolled 1,213 patients with mild-to-severe TBI and assessed the effect of enteral or oral citicoline (2,000 mg/day, for 90 days) on functional and cognitive outcomes (measured by components of the TBI Clinical Trials Network Care Battery) (103)

In ovariectomized rats that were fed fructose, green tea treatment significantly downregulated the hepatic expression of sterol regulatory element-binding protein-1c (SREBP-1c) and its target genes coding for FAS and stearoyl-CoA desaturase 1 (SCD1) as well as the expression of HMGR and efflux proteins (ATP binding cassette superfamily of transporter proteins 1, Abca1) [96]

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