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It is generally accepted that the production of oxidants has to be strictly regulated, and that the ability of cells and organisms to adequately respond to oxidative stress is one of the main regulators of aging and lifespan [111]
Evans RM, Hui S, Perkins A, Lahiri DK, Poirier J, Farlow MR
HDLs benefit to endothelial cells is largely mediated by cell signaling through phosphatidylinositol 3-kinase (PI3K) and Akt and is induced by bioactive lipids and associated proteins on HDL, including lysosulfatide, S1P, and sphingosylphosphorylcholine (SPC) (791,798,806)
Borrelli 2000
Arensman, M
