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Recent studies have shown that high doses of this substance led to a reduction in the acetylation of many lysine residues located on the N-terminal tail of histone H3 [131]
[28] [29] Due to the CNS effects, these drugs should be avoided in infants and young children
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Actually, BAT is an oxidative tissue that, when fully activated, uses fatty acids stored into brown adipocytes to support the activity of the uncoupling protein 1 (Ucp1 or thermogenin) that dissipates the mitochondrial proton gradient to produce heat
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