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Hajime M, Mineo T, Yoshio T

2.6 Serum biochemical analysis The serum levels of TC (total cholesterol), TG (triglycerides), HDL-C (high-density lipoprotein), LDL-C (low-density lipoprotein), ALT/AST (alanine aminotransferase/aspartate aminotransferase), CK (creatine kinase), LDH (layered double hydroxides), and BUN (blood urea nitrogen) were measured using reagent kits (Nanjing Jiancheng Bioengineering Institute, Nanjing, China)

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This suggests that combining amylin and GLP-1 receptor agonism creates additive or synergistic effects on gut motility that increase diarrhea risk