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In the same animal model an improvement of mitochondrial respiration and muscle function has been also observed [51]

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Han M, Yuan S, Zhang J

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Behavioral testing was followed by biochemical analyses on colon, faces, serum, cerebellum, and prefrontal cortex, assessing tryptophan metabolites, serotonin (5-HT) pathway intermediates, neurotransmitters (GABA, glutamate, dopamine, acetylcholine) via UPLC, UPLC-TQD, and ELISA, alongside gut microbiota profiling through 16S r RNA sequencing

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Co-immunization with CCL19 or CCL21 plasmids significantly enhanced protection in challenge, leading to a relative percent survival (RPS) of 78.38% and 72.97% respectively, compared to 40.54% with antigen alone

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