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In colorectal cancer, miR-21 is the target phosphatase, and PTEN is a protein which is overexpressed via curcumin, while in non-small cell lung cancer is under-expressed (Zhang et al., 2010)
It is known that single amino acid alterations in immunogenic peptides can enhance or decrease the binding of the peptide to the MHC class II molecule, causing the differentiation of CD4 T cells into Th1 cells if the binding is strong or into Th2 cells if the binding is weak [389]
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Evidence of the gluten-free and casein-free diet in autism spectrum disorders: A systematic review
