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Physiology 118, 14831490

Development and optimisation of alternative methods and approaches Main gaps identified: high rate of misleading/false genotoxic positives Existing in vitro methods, whilst having a high sensitivity (and thus low false negative rate), have a relatively low specificity and thus high rate of false (misleading) positive results, which typically has led to unnecessary follow-up testing in vivo for the confirmation of these results

Namely, it should be noted that BPC 157 was proved to be efficacious in the ulcerative colitis, both in clinical settings [82,83] as well as in the experimental rats ischemic/reperfusion vascular ulcerative colitis studies [21] and other ulcerative colitis models [10,11,19,33,34,35,36,37,38,39,40,41]

Only half joking here, folks

C.MackieK