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This review aims to synthesize current knowledge on how HIV/SIV infection and ART induce mtDNA damage and how this damage acts as a key indicator and mechanistic driver of associated immunometabolic changes

Starting from the disease-related mechanisms and pathophysiological characteristics of eye blue light injury, this article elucidates the pharmacological mechanisms of various drugs for treating eye blue light injury

Discontinue use if redness, itching, or irritation occurs during or after application, especially after sun exposure

3.5 CB-839 induces autophagy in CLL cell lines Because glutamine flux regulates mammalian target of rapamycin complex 1s kinase activity, which is responsible for autophagy, we assessed the effects of glutaminase inhibition on autophagy as an alternative mechanism of CB-839mediated cell death (3235)

Wang B-j, Wang C-j, Zeng Z-l, Yang Y, Guo S-G