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This chapter explores novel perspectives on the roles of cysteine and homocysteine in pathological processes, delving into their intricate involvement in various disease pathways

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Within the cytosol the accumulating fumarate, similar to the effect of accumulating succinate, results in the inhibition of 2-oxoglutarate and Fe 2+ -dependent dioxygenases that are responsible for the hydroxylation of the -subunit (HIF1) of the HIF-1 complex

Decrease of NADPH (measured at the wavelength of 340 nm) is proportional to GPx activity