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Causes of increased oxidative stress are triggers of hemolytic crisis and include: Fava beans Drugs: antimalarial drugs (e.g., chloroquine, primaquine), sulfa drugs (e.g., trimethoprim-sulfamethoxazole), nitrofurantoin, isoniazid, dapsone, NSAIDs, ciprofloxacin, chloramphenicol Bacterial and viral infections (most common cause): Severe enzymatic deficiency can inhibit respiratory burst activity due to reduced NADPH production in phagocytes

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Summary Our body produces L-carnitine from the essential amino acid lysine via a specific biosynthetic pathway

10.1016/j.mam.2008.08.004 Mol

The heightened interest in MAO-B inhibitors emerged after the revelation that this enzyme could potentially catalyze the formation of neurotoxic compounds from endogenous and exogenous sources