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A third approach, increased bed absorption, which combines the advantages of the two methods referred to previously, has also been developed

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Surprisingly, mice with specific genetic deletion of Gpx1 appear phenotypically normal and with normal life span (Ho et al., 1997), suggesting that there are alternative compensatory mechanisms for H 2 O 2 scavenging in Gpx1 deficiency

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Additionally, plant metabolites and derivatives can regulate ferroptosis by targeting SLC7A11, GPX4, and ACSL4 and influence the immune status in the tumor microenvironment, providing new insights and directions for TCMs in cancer treatment

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