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Elevated CD47 expression on healthy RBCs promotes immunological tolerance and extends circulation duration, whereas reduced CD47 density on elderly or injured RBCs acts as a clearance signal (15, 21, 22)

doi: 10.1016/j.redox.2022.102497 [DOI] [PMC free article] [PubMed] [Google Scholar] [124].Rodrigues E, Mariutti LRB, Mercadante AZ

It is well demonstrated that sensory nerve-derived neuropeptides facilitate lesion fibrogenesis through EMT, FMT, and SMM

In vitro, 5-Amino-1MQ at 30 M in 3T3-L1 adipocytes significantly reduced intracellular 1-MNA levels, confirming NNMT target engagement

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