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A Metabolomics-Based Molecular Pathway Analysis of How the Sodium-Glucose Co-Transporter-2 Inhibitor Dapagliflozin May Slow Kidney Function Decline in Patients with Diabetes

Numerous studies have shown that cancer cells resistant to chemotherapy, radiotherapy, targeted therapy, and even immunotherapy often exhibit high dependence on ferroptosis

These include enhanced fatty acid oxidation, gluconeogenesis, inhibited propionate production from the microbiome, and increased protein breakdown due to the absence of food intake

Owing to the high frequency of cutaneous AEs, it is essential for healthcare professionals to work in multidisciplinary teams, carry out preventive health education for patients, and establish clinical management guidelines