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Description
during hypoxia or glucose starvation, AMPK is activated [138]
M-CSF primarily controls macrophage proliferation and osteoclast survival by stimulating the phosphoinositide-3-kinase/AKT (PI3K/AKT) and extracellular signal-regulated kinase (ERK) pathways [8, 9], while NF-B, PI3K/AKT, and mitogen-activated protein kinase (MAPK) pathways are all activated by RANKL to control osteoclast differentiation [1, 4]
73 KachurS.LavieC
The emerging role and targetability of the TCA cycle in cancer metabolism
Nutrients 12 , 1322 (2020)
