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TB-500 is studied via cytoskeletal protein interaction rather than classical receptor binding: G-actin sequestration modulates actin polymerisation dynamics required for cell motility, migration, and structural remodelling

But from a friend that works at a local surgery its clear that scheduling and giving B12 injections is a massive challenge

That is a story for another time

(2000) showed that daily oral administration of 500 g/kg body weight to obese Zucker rats for 19 days resulted in over 50% reduction in body weight gain (15.8 0.6 g vs

This is why all B12 treatments experts advise not to retest B12 levels after treatment has begun as they are not a reliable guide to whether treatment is being effective
