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Preclinical literature describes it as a peptide involved in maintaining tissue integrity, modulating microcirculation, and the biological response to different types of cellular stress

Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats

Besides their intrinsic scavenger functions, precise localization of various GPXs in tissues argues in favor of specific roles of these enzymes

In HBV-ACLF, reduced levels of testosterone and the free testosterone index are associated with increased disease severity, including higher rates of ascites, hepatic encephalopathy, and overall mortality[65,69]
