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doi: 10.1002/hep.24376

Acetoacetic acid lithium can be used to study metabolic diseases

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This tripeptide is ubiquitous in nature and is produced by every organism from bacteria to plants to animals that derives energy from oxidative phosphorylation and respiration

However, l-serine supplementation does not reduce hyperglycemia in BKS- db/db models despite the improvement in neuropathy phenotypes, suggesting that some forms of diabetic peripheral neuropathy are more directly driven by l-serine deficiency as opposed to hyperglycemia