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However, GSK-3/, a central regulator in lung SCC cells, can promote the expression of GLS and glutamine metabolism by upregulating c-MYC and c-JUN to make cancer cells adapt to chronic mTOR and glycolysis inhibition (85)

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Exerc Sport Sci Rev 30(1):1519 Sandri M, Barberi L, Bijlsma AY, Blaauw B, Dyar KA, Milan G, Mammucari C, Meskers CG, Pallafacchina G, Paoli A, Pion D, Roceri M, Romanello V, Serrano AL, Toniolo L, Larsson L, Maier AB, Munoz-Canoves P, Musaro A, Pende M, Reggiani C, Rizzuto R, Schiaffino S (2013) Signalling pathways regulating muscle mass in ageing skeletal muscle: the role of the IGF1-Akt-mTOR-FoxO pathway

Innate immune cells: A potential and promising cell population for treating osteosarcoma

Specifically, we found that PANC-1 cells had relatively higher levels of GSTM3 expression, whereas MIA PaCa-2 cells had relatively lower levels (Figure 2A)