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Clinically, such insights may pave the way for combination strategies, for example pairing JAK inhibitors with modulators of innate immune activation, thereby improving long-term repigmentation stability

We are focusing on the ketosteroid isomerase activity, which appears to contribute to steroid hormone biosynthesis in mammalian tissues

Ann Genet 43(2):8992 Dervieux T, Furst D, Lein DO, Capps R, Smith K, Walsh M, Kremer J (2004a) Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis

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