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Long-term combined-stack outcomes beyond the trial windows are unstudied

In an interesting study, total flavonoids extract of Rhizoma Drynariae in the concentration of 125 mg/kg inhibited AFB1-induced apoptosis and regulated the expression of PI3K, AKT, Bax and Bcl2 in broilers chickens (427)

It Concentrates Where You Need It Most Once absorbed, ergothioneine is transported via OCTN1 and concentrates in tissues most vulnerable to oxidative stress: Erythrocytes (red blood cells) Eye lens Liver and kidney Brain (particularly mitochondria and nucleus) Skin Bone marrow and semen This preferential accumulation in stress-vulnerable tissues strongly supports its protective role
That means you may need to take it with other drugs

doi: 10.1016/S0304-3940(02)01321-6 24 VolkoffH
