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To test this hypothesis experimentally, we created two truncated APOE M variants: (i) aggregation-prone APOE M -AP with truncated helices N1 and N2 (residues 1-23), and (ii) aggregation-suppressed APOE M -AS with the same truncation, but carrying additional four mutations (R38A, E45A, E49A, and R145A)
Treating major depressive episodes with antidepressants can induce or worsen metabolic syndrome: Results of the METADAP cohort
doi:10.1074/jbc.271.37.22647
[DOI] [PMC free article] [PubMed] [Google Scholar] 468
Ota M, Matsuo J, Ishida I, et al
