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Injections may be administered at a healthcare facility or at home

doi: 10.3390/molecules25122907

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Some ferroptosis-targeting agents have poor pharmacokinetic properties, such as low solubility, high metabolic clearance, low cellular permeability, and short half-lives ( Figure 7 )

Chu et al., 74 implicated eosinophil production of B cell-activating factor belonging to the TNF family (BAFF), IL-6, TGF-, and matrix metalloproteinase 9 (MMP9), whereas Jung et al., 75 identified an alternative pathway involving eosinophil production of IL-1 and lymphotoxins