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MOTS-c has also been investigated under conditions of metabolic stress, in exercise-physiology models, and in relation to cellular senescence contexts in which mitochondrial signalling plays a documented role

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Although the modeled residues of mVP35 OD in our cryo-EM structure (residues 113135) overlap with the coiled coil (residues 60135) in the C-terminal portion of the crystal structure, the trimer could not be superimposed onto the tetrameric mVP35 in our model

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