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However, GH can also exert metabolic actions independent from IGF-1 generation in the liver via activation of the phosphoinositide 3-kinase (PI3 K) and IRS pathways [98]

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Under Article 2 of the Prawo Farmaceutyczne, a medicinal product is defined as any substance or combination of substances presented as having properties for treating or preventing disease in humans, or which may be administered to modify physiological functions

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