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The extracellular matrix components are degraded by macrophage-derived matrix metalloproteinases, (201-203) elastases, and cathepsins (Figure 5) (204)

It's a naturally occurring substance that your body produces every day, and WADA (World Anti-Doping Agency) doesn't prohibit it

Chen, J., Potlapalli, R., Quan, H., Chen, L., Xie, Y., Pouriyeh, S., Sakib, N., Liu, L., & Xie, Y

Other vegetables and fruits, such as cauliflower, red grape, guava, and strawberry also showed similar anticancer properties, but, unlike RGE, the extents of their activities varied from cancer cell lines to lines