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Targeting IL-6 with receptor antagonists shows potential for reducing inflammation and improving glycemic control in T2DM patients, with promising clinical trial results [14]
10.1126/scitranslmed.3007154 Sci Transl Med

SP and HT performed all the experiments

At concentrations below one fourth the C 50 , the effect becomes almost directly proportional to concentration, and the time course of drug effect will follow the exponential decline of concentration

doi: 10.1016/s0300-9084(03)00090-7
