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Qingdao, China: Qingdao University (2012)

doi:10.1016/j.ijpharm.2021.120428 75
Treating obese mice twice a day for a month caused them to gain 10 times less fat than untreated mice and lose 12% of their body weight
The loss of skin elasticity (its ability to bounce back) combined with normal facial expressions causes wrinkles to gradually develop around the eyes

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