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Some patients may experience a transient increase in acne or rosacea-like skin reactions, thought to be related to the effects of vitamin B12 on skin bacteria, though this is uncommon and typically mild

PMCID: PMC10853066

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Energy improvements often appear within 24-48 hours of injection, whereas oral supplements may require weeks of consistent use before effects become apparent

[14] [15] Specialist weight management services (Tier 3) may offer additional pharmacological options, including GLP-1 receptor agonists